Researcher

The University of Gothenburg tackles society's challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

The Department of Molecular and Clinical Medicine, at the Institute of Medicine, conducts translational research primarily on metabolism, diabetes, obesity and cardiovascular disease in order to improve health and healthcare in the community. The overall goal is to create an excellent translational research environment of a very high international standard.

The Romeo laboratory studies the biological and genetic mechanisms underlying metabolic dysfunction-associated steatotic liver disease (MASLD) and its progression to liver fibrosis and cirrhosis. Our research combines human genetics with experimental models to identify disease mechanisms and therapeutic targets. We use state-of-the-art cell culture systems, liver organoids and molecular biology approaches to investigate pathways involved in liver injury and fibrosis.

Duties

The successful candidate will participate in an experimental research project investigating genes involved in susceptibility to liver fibrosis and cirrhosis. The work will involve establishing and maintaining spheroid and organoid cultures derived from liver cell lines and primary human hepatocytes, as well as generating and maintaining stable mammalian cell lines. The successful candidate will also use a range of molecular biology techniques, including DNA and RNA isolation, DNA cloning, transfection, PCR, protein expression analyses, and RNA expression profiling.

In addition, the role includes carrying out biochemical techniques such as immunoblotting (Western blotting), immunoprecipitation, subcellular fractionation, and siRNA-mediated gene silencing. The project further involves conducting metabolic flux experiments using radioactive tracers, as well as immunocytochemistry and in situ hybridisation experiments. R- and Linux-based computational tools will be used to analyse genetic and genomic datasets.

The work includes documenting, analysing, and presenting experimental results and actively participating in regular laboratory meetings and scientific discussions. The position provides an opportunity to gain practical experience in translational liver research and experimental disease modelling.

Qualifications

The successful applicant should have a background in biomedicine, molecular biology, biotechnology, cell biology, or another relevant life science discipline. Previous experience with organoid and/or spheroid culture, or liver biology, is required, as is practical experience in molecular biology. A good command of spoken and written English is also essential for the position.

Experience in omics analysis is considered meritorious, as is experience with mammalian cell culture, including spheroids and/or organoids and the generation of stable cell lines. Experience with molecular biology techniques such as DNA and RNA extraction, cloning, PCR, transfection, and gene expression analysis will be considered an advantage. Similarly, experience with biochemical techniques, including Western blotting, immunoprecipitation, and immunocytochemistry, is desirable. Experience with RNA interference (siRNA) and the analysis of biological data using R and/or Linux-based environments is also considered meritorious. Previous experience in liver biology, metabolism, or experimental disease models will be viewed favorably.

Great emphasis will be placed on personal suitability. The successful applicant should be motivated, well organized, able to work both independently and as part of a research team and have a genuine interest in experimental biomedical research.

Employment

Employment type: Fixed-term
Extent: 100%
Location: Institute of Medicine, Gothenburg
Start date: According to agreement, the employment runs until December 31, 2026.

Contact information for the post

Stefano Romeo
Professor/Specialized Physician
+46(0)768-67 26 34
stefano.romeo@wlab.gu.se

Malin Levin
Head of Department
Malin.Levin@wlab.gu.se

Unions

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/en/work-at-the-university-of-gothenburg/how-to-apply-for-a-position#collective-agreement-and-union-representatives

Information for International Applicants
Visit the webpage Join us - jobs and career for more information on the Institute of Medicine and what opportunities we have for you. Discover our world-class research and research infrastructure, as well as what the benefits are for you and your family.

Application

To apply for a position at the University of Gothenburg, you have to create an account in our recruitment system. Submit your application via the University of Gothenburg's recruitment portal by clicking the "Apply" button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.

Please enclose PhD certificate with the application.

Applications must be received by: 2026-09-01.

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden's regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.