Postdoctoral studies in personalization of standard-of-care chemotherapeutics (scholarship)

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The Department of Oncology-Pathology conducts basic, translational, and clinical research together with educational activities related to cancer. We are recruiting a postdoctoral researcher to join the Rudd group and work under the supervision of Research Specialist Si Min Zhang, who leads a newly established research program. The research environment is located at SciLifeLab Campus Solna, a state-of-the-art national infrastructure for life science that fosters cutting-edge, multidisciplinary collaboration at both national and international levels.
Duties
Differentiation therapy induces cancer cells into terminally differentiated, non-proliferating state, and has revolutionized the treatment of the once deadly acute promyeloid leukemia (APML). Nevertheless, identifying and mechanistic deciphering of factors controlling differentiation therapy response remains critical for 1) treating resistant/refectory APML, 2) individualized treatment regimen design to mitigate excessive side effects, and 3) sensitizing non-APML cancer to differentiation therapy. Here we are seeking a highly motivated postdoctoral researcher to join our team to identify and develop approaches to improve differentiation therapy, in the disease context of acute myeloid leukemia and beyond.
Entry requirements
Postdoctoral scholarships may be established for foreign researchers who pursue their merit in Sweden. A foreign researcher is a person living in another country who comes to Sweden with the intention of only staying in Sweden for all or part of their postdoctoral education at KI. Persons who are resident in Sweden and/or have carried out all or part of their academic education at KI or some other educational institution in Sweden cannot be considered for scholarships. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four-year period following the receipt of a doctoral degree or equivalent.

To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate, or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post-doctoral education.

Ideal candidates will demonstrate competence in

• General cell and molecular biology techniques, including but not limited to RT-qPCR, Western blotting, high content imaging analysis, flow cytometry, genetic perturbation strategies, lentiviral vector construction. Prior experience in bioinformatics will be highly advantageous.
• Keen interest in translational research in acute myeloid leukemia, differentiation therapy, glioma and related field of research.
• Independent project management. The candidate will lead the project, and should be able to plan, execute, analyze, and present study results independently.
• First author publication/preprint.
• Effective communication skills, both verbal and written. Prior experiences of international conference presentation and grant preparation is a plus.

Emphasis will be also placed on personal suitability, fitting well into the current research group.
What do we offer?
A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Students and employees have free access to our modern gym facilities with trained staff on site.

Location: Science For Life Laboratory, Solna
Type of scholarship
The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.
Application process
An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

KI applies individual and differentiated salary setting in accordance with our collective agreements RALS and RALS-T

The application is to be submitted on the Varbi recruitment system. Apply at the latest 31 st July.
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