Clinical Trial Manager to Karolinska University Hospital

Clinical Trial Manager to Karolinska University Hospital

Join an international research collaboration at the forefront of reconstructive surgery and post amputation pain. As Clinical Trial Manager, you will play a key role in coordinating two international clinical trials across leading research hospitals, working at the intersection of clinical research, bionics and prosthetics.

You are offered

• a collaborative and supportive leadership approach where we value every individual and strive to provide you with the best possible conditions for your continued professional development
• a rewarding role at one of the world's leading university hospitals, where you will help shape the future of healthcare, research and education.

About the employment

The position is attached to the international research project International Study on Surgical Reconstruction for Post-Amputation Pain, funded by the Promobilia Foundation.

The project comprises two parallel randomized controlled trials comparing two reconstructive nerve surgery techniques, Targeted Muscle Reinnervation (TMR) and Regenerative Peripheral Nerve Interface (RPNI), for the treatment and prevention of pain after amputation.

The studies are coordinated from Karolinska University Hospital and conducted in collaboration with nine leading international hospitals, including the Prometei Pain Rehabilitation Center in Ukraine and collaborating surgeons and research teams in Italy, the USA, Australia, Canada, Chile, and the UK.

The research spans the fields of reconstructive surgery, bionics, prosthetics, and post-amputation pain.
The Clinical Trial Manager will:

• Coordinate data collection from participating international sites in accordance with the trials' ethics approvals and applicable quality standards, including ISO 14155 where applicable.
• Serve as a liaison between the coordinating center at Karolinska University Hospital and participating international clinical and research sites.
• Support and coordinate biannual monitoring activities across participating sites.
• Contribute to ethics applications, amendments, and study documentation as the project develops.
• Contribute to data management and statistical analysis together with the project's statistician.
• Contribute to the preparation of scientific manuscripts, reports, and conference presentations.
• Support the overall coordination and documentation of the international clinical trials.

The position is a 15% fixed-term project employment, externally funded by the Promobilia Foundation, within the project International Study on Surgical Reconstruction for Post-Amputation Pain. The planned project period is 2026-2029.
We are looking for you who

• takes responsibility for their tasks, independently structures their approach, and drives processes forward
• works effectively with others, communicates in a responsive and constructive manner, and contributes to productive collaboration
• plans, organizes, and prioritizes work effectively and is able to establish and meet timelines
• works carefully with a strong awareness of objectives and quality standards and places great importance on meeting these standards
• works effectively with complex issues, analyzes problems systematically, and identifies appropriate solutions

Qualifications

Required:

• An MSc in biomedical engineering, clinical research, or a closely related field.
• Documented experience with clinical study documentation, research protocols, ethics applications, or related clinical research activities.
• Knowledge of relevant clinical research quality and regulatory frameworks, such as ISO 14155 and/or the Medical Device Regulation (MDR).
• Documented research experience in bionics and/or pain related to sensorimotor impairment.
• Excellent written and spoken English.

Preferred:

• Research experience in prosthetics and bionics, including myoelectric pattern recognition, prosthetic control, and/or electrical stimulation related to osseointegrated prostheses.
• Proficiency in quantitative methods and data analysis using tools such as MATLAB, Python, or R.
• A track record of scientific writing and publication.
• Experience with cross-institutional and international research collaboration, for example through research projects, exchange programs, or collaborations with other universities.
• Additional languages relevant to the project's international collaborations, for example Italian.

About the recruitment process

Selection and interviews may take place on an ongoing basis throughout the application period.

When applying, you are required to attach your CV. Instead of a cover letter, we ask you to answer selection questions and briefly explain why you are a good fit for the role. Answering the questions is a prerequisite for your application to be considered complete.

We warmly welcome your application - Together, we are Karolinska!

For appointments to positions involving the care of children and young people, the successful candidate will be subject to a check against the Swedish criminal records and suspicion registers. Read more about the recruitment process and the checks carried out at Karolinska here.

As an employee at Karolinska University Hospital, you may be assigned a wartime placement. Read more about what this means here.

If you are currently or have previously been employed by Region Stockholm, we will obtain internal references from your current or previous manager if you are considered for employment.

For permanent positions, a probationary period may apply.

About Karolinska University Hospital

At Karolinska University Hospital, we are proud to be one of the world's leading university hospitals. In addition to our special responsibility for highly specialised healthcare in the Stockholm region, our main mission is to educate the healthcare professionals of tomorrow together with Karolinska Institutet and conduct world leading research, while continuing to develop healthcare for the benefit of our patients. We work across a wide range of fields and professions.

Our vision: We will cure and relieve tomorrow what no one can cure or relieve today.

Learn more about us at karolinska.se and follow us on social media!

Theme Acute and Reparative Medicine

Theme Acute and Reparative Medicine consists of six medical units: Emergency Medicine, Trauma, Acute Surgery and Orthopaedics, Plastic and Craniofacial Surgery, Ear, Nose and Throat, Hearing and Balance, and Transplantation.

Read more about us here.

Applying for a position at Region Stockholm

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