Researcher, development of cholinesterase inhibitors in cancer treatment

Om jobbet

The University of Gothenburg tackles society's challenges with diverse knowledge. 58 000 students and 6800 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract researchers and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

The Department of Chemistry and Molecular Biology conducts high-quality research and education in chemical sciences and molecular life sciences. Our research and education focuses on a deep understanding of chemical and biological processes in cells and in the environment. We are responsible for postgraduate education in the subject area Natural Sciences with a focus on chemistry, biophysics, biology and educational science. In addition, the department hosts educational programmes in molecular biology, bioinformatics, chemistry, organic chemistry and medicinal chemistry, as well as Bachelor's Programme in Pharmacy/Dispensing Pharmacists. The department is an international environment with interdisciplinary collaborations in both research and education and contributes strongly to the University of Gothenburg's top ranking in life science. We are centrally located in Natrium, Medicinareberget, Gothenburg.

The position is linked to the research group in theoretical biochemistry. In the research group, advanced research on protein structures and protein complexes, protein-ligand interactions and drug discovery is performed. The group utilizes advanced computational chemistry and AI based methodologies.

Duties

Work tasks include in silico based develeopment and screening of inhibitors towards acetyl and butyryl cholinesterases, such as MD simulations, AI-based screening, docking and ligand design. The candidate will furthermore test promising drug candidates against cancer cells with upregulated AchE activity.

Qualifications

Eligable for the postion:

• PhD in microbiology, molecular biology, theoretical biochemistry, or equivalent, obtained in the last 3 years.

Requirements for the position:

• At least 3 years of experience, including scientific publications, of: the use of advanced computational chemistry tools, primarily the Schrödinger package for docking and MD simulations; conducting in-vitro experiments; and studies of acetyl- and butyryl-cholinesterase.
• Experience usage of supercomputer clusters for docking and simulations.

Meritious for the position:

• Experience in presenting research at scientific conferences and in research groups.
• Ability to collaborate and experience in supervision of students.
• Very good oral and written proficiency in English.

Employment

The employment as researcher is a fixed term, fulltime,100 % during 7 months at the Department of Chemistry and Molecular Biology.

Contact information for the post

If you have any questions about the position, please contact professor: Leif Eriksson, e-mail: leif.eriksson@chem.gu.se

Unions

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande

Application

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system, Reach mee,. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application.

The application must include

• Résumé/CV
• Cover Letter
• Contact information of at least two references,
• Copy of degree certificate, and other certificates/grades that you wish to be considered. The qualifications claimed must be documented, certified and translated into English.

All attachments must be labelled in a way that clearly shows their content.

Applications must be received by:2025-12-18

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden's regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.